Educational Resources
Case-Based Learning
Topic: ARIA MRI Case-Based Learning
Viewing time: 50 minutes
Learning Objectives:
•Understand the appearance of two subtypes of ARIA on MRI: ARIA-E and ARIA-H.
•Explore optimal MRI sequences used to detect ARIA.
•Understand how to differentiate ARIA findings from other potential mimics, such as incomplete water suppression, subarachnoid hemorrhage, and vascular structures.
•Build awareness on how ARIA findings may impact patient management and potential treatment modifications.
Speaker: Dr. Jerry Barakos Sutter Health Hospitals/Clario, San Francisco, California
Expert Video Lectures
In this video series, neuroradiologist Dr. Tammie Benzinger and neurologist Dr. Marwan Sabbagh discuss their experiences in detecting and monitoring amyloid-related imaging abnormalities (ARIA), current working practices, and defining workflows for optimal care.
Speaker: Dr. Tammie Benzinger, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA
Speaker: Dr. Marwan Sabbagh, Barrow Neurological Institute, Phoenix, Arizona, USA
Topic: Introduction to ARIA
Viewing time: approximately 6 minutes
• What causes ARIA?
• What is the role of cerebral amyloid angiopathy (CAA)?
• What are the risk factors for ARIA?
• Is there a connection between CAA and APOE ε4?
• Can you get ARIA more than once?
Topic: Detecting and monitoring ARIA
Viewing time: approximately 18 minutes
• What is the role of MRI in detecting ARIA?
• What about patients with a pacemaker?
• Does the magnet size of the MRI matter?
• What sequences should the report detail for ARIA?
Topic: Defining a workflow for the detection and monitoring of ARIA (US perspective)
Viewing time: approximately 9 minutes
• How should the results of the MRI scan be communicated to a neurologist?
• Is an ARIA protocol/imaging protocol going to become available?
• Why is grading the severity of ARIA important?
• Does the radiographic severity of ARIA and clinical severity correlate?
• How long does ARIA take to resolve on MRI?
• Why quantify microhemorrhages at baseline and how should these be reported to the neurologist?
Topic: Clinical practice decision-making and considerations
Viewing time: approximately 10 minutes
• How do we treat patients with symptomatic ARIA who present to the emergency room?
1-hr Educational Webinar: Understanding Amyloid-Related Imaging Abnormalities: a Case-Based Conversation
Viewing time: approximately 55 minutes
Speaker: Dr. Tammie Benzinger, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA
Speaker: Dr. Jerry Barakos Sutter Health Hospitals/Clario, San Francisco, California
Speaker: Dr. Alireza Atri Banner Sun Health Research Institute, Phoenix, Arizona
Topic: What are amyloid-related imaging abnormalities (ARIA) and how do they arise?
Viewing time: approximately 10 minutes
• Learning objective: Enhance your understanding of ARIA and its hypothesized pathophysiology in the context of Alzheimer’s disease and for patients being treated with monoclonal antibodies that remove amyloid plaque.
Speaker: Dr. Tammie Benzinger, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA
Topic: How do we detect ARIA and what do we need to be aware of?
Viewing time: approximately 15 minutes
• Learning objective: Learn how ARIA is detected and diagnosed, with consideration towards appropriate imaging sequences and the potential need for differential diagnoses.
Speaker: Dr. Jerry Barakos Sutter Health Hospitals/Clario, San Francisco, California
Topic: Case study discussion: How do we monitor and manage ARIA?
Viewing time: approximately 30 minutes
• Learning objective: Gain in-depth knowledge of how ARIA is monitored and managed through the exploration of case studies.
Speaker: Dr. Jerry Barakos Sutter Health Hospitals/Clario, San Francisco, California
Speaker: Dr. Alireza Atri Banner Sun Health Research Institute, Phoenix, Arizona